This applied psychoanalytic presentation by W. Scott Griffies, MD, explores the phenomenon of murder-suicide in post-Katrina New Orleans. This presentation utilizes an object relational framework to understand the multidetermined causes of the murder-suicide. It highlights how disasters can bring individuals together in desperate situations, destabilize social connections, and exacerbate avoidant defenses through increased substance abuse. Furthermore, it reveals how such traumatic events can reopen past wounds, including PTSD and experiences of abuse, creating a mental health crisis that extends far beyond the initial impact of the storm. It also underscores the significance of interpersonal containment of toxic projections in the aftermath of a disaster, particularly for individuals with intrapsychic vulnerabilities.